Products

Kisspeptin is a pivotal neuropeptide that regulates the reproductive system, hailed as the **"switch that initiates puberty"** and the **"commander-in-chief of the reproductive axis."**
I. Basic Information
Full Name: Kisspeptin (formerly known as Metastin)
Encoding Gene: KISS1
Receptor: KISS1R (formerly known as GPR54)
Major Forms:
KP-54: Full-length form; the primary circulating form
KP-10: Minimal active unit; frequently used in research
II. Core Physiological Functions
1. Regulation of the Reproductive Center (Primary Function)
Action Pathway:
Kisspeptin → Stimulates GnRH → Promotes LH/FSH release → Sex Hormones (Testosterone / Estrogen)
Initiation of Puberty: Kisspeptin levels are low prior to puberty, then surge dramatically during puberty
Maintenance of Fertility: Regulates ovulation, spermatogenesis, and sexual function
Hormonal Feedback: Mediates both positive and negative feedback effects of estrogen/progesterone on the central nervous system
2. Metabolism-Reproduction Link
Energy Sensitivity: Responsive to Leptin and Insulin
Famine Signaling: In conditions of energy deficit, Kisspeptin levels decline → Suppression of reproductive function (amenorrhea / infertility)
3. Other Functions
Tumor Suppression: Originally identified as a tumor metastasis suppressor factor
Maintenance of Pregnancy: Levels surge during pregnancy; involved in placental function
Neuroprotection: Exhibits anti-oxidant and anti-apoptotic properties
III. Clinical Significance
Hypofunction: Hypogonadotropic Hypogonadism (IHH), Infertility
Hyperfunction: Central Precocious Puberty (CPP)
Associated Conditions: Polycystic Ovary Syndrome (PCOS), Amenorrhea
Applications: Assisted Reproductive Technology (IVF), Infertility Treatment, Diagnosis of Disorders of Sexual Development

Factory

Packing & Delivery

We have cooperated with experienced shipping forwarders for many years, they arrange the shipment. No matter by express, by air or by sea, we will track the course of the goods all the way, to make sure goods arrive at you on time and in good condition.