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PINEALON
Pinealon (Pineal Peptide)
Full Name: Glu-Asp-Arg (EDR) Tripeptide
Core Positioning: Neuroprotection + Brain Anti-Aging + Sleep Rhythm Regulation Peptide
I. Basic Attributes
Structure: A synthetic short peptide consisting of 3 amino acids (Glutamic Acid - Aspartic Acid - Arginine)
Source: Russian research on brain bioregulatory peptides
Characteristics: Easily penetrates the blood-brain barrier; acts directly on brain cells
II. 5 Core Functions
1. Potent Neuroprotection (Primary Function)
Scavenges Reactive Oxygen Species (ROS), enhances the antioxidant enzyme SOD, and mitigates cerebral oxidative stress
Inhibits ERK1/2 and Caspase-3 pathways, reducing neuronal apoptosis and brain injury
Provides resistance against hypoxia and glutamate excitotoxicity, protecting brain cells
2. Brain Anti-Aging & Cognitive Enhancement
Regulates neuronal gene expression, delays brain aging, and improves memory and learning capabilities
Increases BDNF (Brain-Derived Neurotrophic Factor) levels, enhancing synaptic plasticity
Alleviates "brain fog," declining concentration, and mental fatigue
3. Regulation of Sleep & Circadian Rhythms
Modulates pineal gland-related genes, improves sleep quality, and corrects biological clock disturbances
Promotes the balance of serotonin and melatonin, aiding sleep and reducing anxiety
4. Emotional Stability
Enhances serotonin synthesis, providing anti-anxiety and anti-depressant effects, and stabilizing mood
Reduces stress responses, alleviating chronic fatigue and low mood
5. Mitochondrial & Cellular Energy
Optimizes mitochondrial energy production within neurons, boosting mental energy and clarity of thought
III. Synergistic Combinations with Other Peptides of Interest
Pinealon + Epitalon
The "Golden Combination": Brain Protection + Systemic Anti-Aging (Telomeres) + Dual Pineal Gland Regulation
Pinealon + MOTS-c
Dual Mitochondrial Action: Brain Energy + Systemic Metabolism + Anti-Aging
Pinealon + BPC-157
Neuronal Repair + Systemic Tissue Repair; suitable for brain injury recovery and post-operative rehabilitation
Pinealon + Oxytocin
Dual Emotional Stability: Stress reduction, anti-anxiety effects, sleep aid, and improved social well-being
Pinealon + NAD+/NMN
Cellular Anti-Aging + Neuro-Energy: Comprehensive Anti-Aging and Neuroprotection
IV. Usage (For Research Reference)
Injection: 1–2 mg/day (subcutaneous); administered in cycles of 10–20 days.
Oral Administration: 0.2 mg per dose; taken twice daily.
Cycle: Repeat the regimen every 3–6 months.
V. One-Sentence Summary
Pinealon = Neurocellular Shield + Brain Anti-Aging Agent + Sleep & Mood Regulator
Long-term neuroprotection, memory enhancement, mood stabilization, sleep regulation, and anti-neuroaging.

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